JAMA Otolaryngology Head and Neck Surgery 2020-08-01

JAMA Otolaryngology–Head & Neck Surgery

Publicatie 01-08-2020


Mission Statement: JAMA Otolaryngology–Head & Neck Surgery provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinical, translational, and population health research from an array of disciplines. We place a high priority on strong study designs that accurately identify etiologies, evaluate diagnostic strategies, and distinguish among treatment options and outcomes. Our objectives are to (1) publish original contributions that will enhance the clinician’s understanding of otolaryngologic disorders, benefit the care of our patients, and stimulate research in our field; (2) forecast important advances within otolaryngology–head and neck surgery, particularly as they relate to the prevention, diagnosis, and treatment of disease through clinical and translational research, including that of the human genome and novel imaging techniques; (3) address questions of clinical outcomes and cost-effectiveness that result from clinical intervention, which grow in importance as health care providers are increasingly challenged to provide evidence of enhanced survival and quality of life; (4) provide expert reviews of topics that keep our readers current with true advances and also to provide a valuable educational resource for trainees in the several disciplines that treat patients with diseases of the head and neck; (5) serve as a forum for the concerns of otolaryngologists such as socioeconomic, legal, ethical, and medical issues; (6) provide helpful critiques that enable contributing authors to improve their submissions. We encourage a concise presentation of information and employ an abstract format that efficiently assesses validity and relevance from a clinical perspective. This approach promotes succinct yet complete presentation for our readers and electronic information resources. We believe this approach typifies the commitment of JAMA Otolaryngology–Head & Neck Surgery to providing important information that is easily interpreted by its diverse readership.

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Carotid Space Masses With Liver and Bone Metastases

Wangaryattawanich P, Kim S, Rath TJ.

Publicatie 01-08-2020


A young adult nonsmoker patient presented with a palpable left neck mass; contrast-enhanced computed tomography showed a large avidly enhancing mass in the neck and enhancing masses in the liver. What is your diagnosis?

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Decontamination Methods for Reuse of Filtering Facepiece Respirators

Su-Velez BM, Maxim T, Long JL, et al.

Publicatie 01-08-2020


This Special Communication summarizes studies describing various methods of decontamination to allow safe reuse of N95 respirators.

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Targeted Oncogene Therapy Before Surgery in Pediatric Patients With Advanced Invasive Thyroid Cancer

Kazahaya K, Prickett KK, Paulson VA, et al.

Publicatie 01-08-2020


This review discusses the potential role of oncogene-specific targeted therapy as neoadjuvant treatment for children and adolescents with advanced invasive thyroid cancer at diagnosis.

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Evolution of Loss of Smell or Taste in COVID-19

Boscolo-Rizzo P, Borsetto D, Fabbris C, et al.

Publicatie 01-08-2020


This prospective survey-based study examines the clinical course of the loss of sense of smell and taste in a case series of mildly symptomatic patients with SARS-CoV-2 infection.

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Treatment Recommendations for Persistent Smell and Taste Dysfunction Following COVID-19

Levy JM.

Publicatie 01-08-2020


In their study, “Evolution of Altered Sense of Smell or Taste in Patients With Mildly Symptomatic COVID-19,” Boscolo-Rizzo et al present the first insight into olfactory outcomes following coronavirus disease 2019 (COVID-19) among a population of Italian patients with otherwise mild disease. This cohort was previously used to establish alterations in self-reported sense of smell and taste as important symptoms of COVID-19, finding a prevalence of 64.4% among the 202 patients treated at home for mildly symptomatic disease. In this important follow-up study, approximately 90% of participants experienced improved olfactory symptoms 4 weeks following initial diagnosis, with 48.7% reporting complete resolution of symptoms during this time. This encouraging finding is consistent with other preliminary reports of high rates of olfactory recovery among patients with COVID-19, but is in stark contrast to other forms of postinfectious smell and taste dysfunction, which are characterized by recalcitrant symptoms in 40% to 60% of those affected.

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Progressive Trigeminal Hypoesthesia

Bourdillon AT, Tower JI, Edwards HA.

Publicatie 01-08-2020


A 34-year-old man presents with progressive lower lip and chin numbness and ipsilateral facial fullness with trigeminal nerve deficit; magnetic resonance imaging reveals a T1 isointense, T2 hyperintense lesion. What is your diagnosis?

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Exercise Prehabilitation—Supporting Recovery From Major Head and Neck Cancer Surgery

Twomey R, Culos-Reed S, Dort JC.

Publicatie 01-08-2020


This Viewpoint highlights the potential role of exercise prehabilitation in patients scheduled to undergo major surgery for head and neck cancer.

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Hearing Preservation in Patients Who Undergo Labyrinthectomy and Translabyrinthine Procedures

Reddy P, Yan F, Liu YF, et al.

Publicatie 01-08-2020


This systematic review assesses whether hearing loss occurs after any disruption of the inner ear for surgical treatment of Meniere disease and removal of cholesteatoma or vestibular schwannoma.

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Laryngectomy Care in the COVID-19 Era

Sarsfield E, Montano M, Choi K, et al.

Publicatie 01-08-2020


This Patient Page describes the particular risks the coronavirus disease 2019 pandemic presents for patients with a laryngectomy and how best to mitigate risk.

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Prevalence and Severity of Hearing Loss in the Older Old Population

Sharma RK, Lalwani AK, Golub JS.

Publicatie 01-08-2020


This cross-sectional study characterizes the prevalence of age-related hearing loss in people 80 years and older using data from the National Health and Nutrition Examination Survey.

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A Pigmented Lesion on the Palate

Stanbouly D, Canterbury CR, Peters SM.

Publicatie 01-08-2020


A 57-year-old African American man presents with an occasionally pruritic, brown pigmented lesion on the hard palate that histologically demonstrates soft tissue covered by benign-appearing stratified squamous epithelium. What is your diagnosis?

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Lateral Vocal Fold Fullness in a Patient With Heavy Voice Use

Choi JS, Chopra S, O’Dell K.

Publicatie 01-08-2020


A 45-year-old male professional voice user presents with dysphonia, throat tightness, and voice roughness; laryngoscopy revelated a firm lesion in the left paraglottic space extending to the lateral aspect of the true vocal fold. What is your diagnosis?

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Grasping What We Cannot Touch

McCoul ED.

Publicatie 01-08-2020


This Viewpoint describes techniques by which otolaryngologic physical examination can be performed when the patient is not physically present with the examiner.

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Multimodal Analgesia and Perioperative Opioid Requirements in Head and Neck Surgery With Free Flap

Vu CN, Lewis CM, Bailard NS, et al.

Publicatie 01-08-2020


This case-control study examines the association between multimodal analgesia administration and perioperative opioid requirements in patients undergoing head and neck surgery with free flap reconstruction and investigates whether multimodal analgesia alters the duration of stay in the postanesthesia care unit.

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Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019

Mercante G, Ferreli F, De Virgilio A, et al.

Publicatie 01-08-2020


This survey study of patients with coronavirus disease 2019 investigates the presence of sinonasal manifestations at the onset of the disease to achieve an earlier diagnosis.

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Development of Eruptive Squamous Atypia 2 Weeks Post Fractional CO 2 Laser Resurfacing

Meltzer OA, Liem WH, Daines SM.

Publicatie 01-08-2020


This case report describes a woman in her 60s with a previous history of basal cell carcinoma who presented with multiple wart-like lesions that erupted on both her cheeks 2 weeks after full-face fractional CO2 laser resurfacing.

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Marketing Claims About Using Hearing Aids to Forestall or Prevent Dementia

Blustein J, Weinstein BE, Chodosh J.

Publicatie 01-08-2020


This cross-sectional study surveys the websites of 16 leading hearing aid brands for claims that using hearing aids can forestall or prevent dementia.

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Missing Co–First Authorship Notice

Publicatie 01-08-2020


In the article titled “Severe Facial-Disfiguring Xeroderma Pigmentosum With Rapidly Progressing Malignant Tumors,” published in the February 2019 issue of JAMA Otolaryngology–Head & Neck Surgery, indication of co–first authorship was missing. Authors Tao Zan, MD, PhD, and Xin Huang, MD, are co–first authors of this article. The article has been corrected online.

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Association of Sarcopenia With Outcomes of Surgery or Radiotherapy Among Patients With Oropharyngeal SCC

Olson B, Edwards J, Stone L, et al.

Publicatie 01-08-2020


This cohort study examines whether primary surgical resection or definitive radiotherapy is associated with improved survival for patients with sarcopenia and localized oropharyngeal squamous cell carcinoma (SCC).

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Host Factors Independently Associated With Prognosis in Patients With Oral Cavity Cancer

Valero C, Zanoni DK, Pillai A, et al.

Publicatie 01-08-2020


This cohort study evaluates the host factors associated with prognosis in patients with oral cavity squamous cell carcinoma and their interactions for development of a numerical index that quantifies their prognostic capacity.

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Correcting Magnesium Disorders—A High-Value Target?—Reply

Liu R, Gourin CG, Russell JO.

Publicatie 01-08-2020


In Reply We thank Liang and Chen for their interest in our study analyzing the factors associated with development of postthyroidectomy hypocalcemia using the United States MarketScan Commercial Claim and Encounters database. We thank the editor for this opportunity to respond to the issues raised in the letter and to further clarify aspects of our methodology.

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Nasopharyngeal Mucocele Following Balloon Eustachian Tuboplasty

Lee S, Kim S, Choi S, et al.

Publicatie 01-08-2020


This case report describes a man in his 50s who developed nasopharyngeal mucocele following balloon eustachian tuboplasty that required surgical treatment.

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Correcting Magnesium Disorders—A High-Value Target?

Liang K, Chen Z.

Publicatie 01-08-2020


To the Editor We would like to thank Liu et al for their study analyzing the factors associated with the development of hypocalcemia after total thyroidectomy. They found magnesium disorders to be a strong independent risk factor associated with both short- and long-term hypocalcemia postoperation, highlighting the value of treating hypomagnesemia as a modifiable target to reduce the incidence of hypocalcemia after total thyroidectomy.

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Otolaryngology Residency Match During the COVID-19 Pandemic

Xie DX, Hillel AT, Ward BK.

Publicatie 01-08-2020


This Viewpoint identifies concerns and potential solutions for aspiring otolaryngology–head and neck surgeons and otolaryngology departments in the residency match process during the COVID-19 pandemic.

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Evaluation of PAP as an Outcomes Predictor of Hypoglossal Nerve Stimulation Surgery in Patients With OSA

Seay EG, Keenan BT, Schwartz AR, et al.

Publicatie 01-08-2020


This cohort study evaluates the use of therapeutic nasal positive airway pressure response during drug-induced sleep endoscopy as a predictor of the success of subsequent hypoglossal nerve stimulation.

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Factors Associated With Health-Related Quality of Life in Patients With Facial Palsy—Reply

Bruins TE, van Veen MM, Dijkstra PU.

Publicatie 01-08-2020


In Reply Lin and Sol refer to some limitations in our study. First we fully agree that the study, as every study, has its limitations. They assume that facial palsy may influence socioeconomic status and therefore health-related quality of life (HRQoL). We performed additional univariate analyses to explore this assumption. We found no significant associations between facial palsy severity (Sunnybrook score) and socioeconomic status operationalized as income, occupational status, and education. In addition, no association was found between the Sunnybrook score and age (≤65 and >65 years). A higher facial clinimetric evaluation scale (FaCE) total score was found for people aged 65 years or younger, people who worked, and those with a higher Sunnybrook score. In multivariable analysis the Sunnybrook score remained the only statistical predictor (results available on request to the corresponding author). Based on our additional analyses we cannot confirm the assumption of Lin and Sol, but future longitudinal research should be performed. Regarding generalizability of our results to the working population, they refer to a study by Nellis et al that included patients with a mean (SD) age of 52.0 (14.9) years. Based on a normal distribution it can be calculated (mean; SD, 2) that 95% of participants in that study had an age between 23 and 81 years, not the age range of the working population Lin and Sol refer to (15-64 years). Furthermore, not only ours, but also other studies with a lower age range found a weak but significant association between age and HRQoL: mean (SD) age of 47.0 (16.0) years (β = −0.2) and 48.6 (16.7) years (r = −0.1), respectively. Taking the above into account, the association between age and HRQoL needs further research in different age groups of persons with facial palsy.

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Factors Associated With Health-Related Quality of Life in Patients With Facial Palsy

Lin S, Sol K.

Publicatie 01-08-2020


To the Editor Bruins et al performed a cross-sectional analysis of a sample of patients with facial palsy who had undergone surgery to ascertain the association between socioeconomic and personality factors with health-related quality-of-life (HRQoL). The authors reported that age, bilateral facial palsy, severity of facial palsy, mental distress, and personality traits were associated with HRQoL in patients with long-standing facial palsy.

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Prevalence and Population Estimates of Obstructive Eustachian Tube Dysfunction in US Adolescents

Kim AS, Betz JF, Goman AM, et al.

Publicatie 01-08-2020


This cross-sectional cohort study uses census data to approximate population estimates of obstructive eustachian tube dysfunction among US adolescents.

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