JAMA Otolaryngology Head and Neck Surgery 2024-04-01

JAMA Otolaryngology–Head & Neck Surgery

Publication date 01-04-2024


Mission Statement: JAMA Otolaryngology–Head & Neck Surgery provides timely information for physicians and scientists concerned with diseases of the head and neck. Given the diversity of structure and function based in this anatomic region, JAMA Otolaryngology–Head & Neck Surgery publishes clinical, translational, and population health research from an array of disciplines. We place a high priority on strong study designs that accurately identify etiologies, evaluate diagnostic strategies, and distinguish among treatment options and outcomes. Our objectives are to (1) publish original contributions that will enhance the clinician’s understanding of otolaryngologic disorders, benefit the care of our patients, and stimulate research in our field; (2) forecast important advances within otolaryngology–head and neck surgery, particularly as they relate to the prevention, diagnosis, and treatment of disease through clinical and translational research, including that of the human genome and novel imaging techniques; (3) address questions of clinical outcomes and cost-effectiveness that result from clinical intervention, which grow in importance as health care providers are increasingly challenged to provide evidence of enhanced survival and quality of life; (4) provide expert reviews of topics that keep our readers current with true advances and also to provide a valuable educational resource for trainees in the several disciplines that treat patients with diseases of the head and neck; (5) serve as a forum for the concerns of otolaryngologists, such as socioeconomic, legal, ethical, and medical issues; (6) provide helpful critiques that enable contributing authors to improve their submissions. We encourage a concise presentation of information and employ an abstract format that efficiently assesses validity and relevance from a clinical perspective. This approach promotes succinct yet complete presentation for our readers and electronic information resources. We believe this approach typifies the commitment of JAMA Otolaryngology–Head & Neck Surgery to providing important information that is easily interpreted by its diverse readership.

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Error in Discussion Section

Publication date 01-04-2024


In the article titled “Partial Thyroidectomy With Incidental Metastatic Lymph Nodes” published on November 16, 2023, in JAMA Otolaryngology–Head & Neck Surgery, there was an error in the Discussion section that indicated microscopic extrathyroidal extension occurred in 122 of 74 patients (30%). It now correctly reads 22 of 74 patients. This article was corrected online.

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Monitoring Thyroglobulin Following Total Thyroidectomy After Lobectomy

TL Chow

Publication date 01-04-2024


To the Editor The article “Partial Thyroidectomy With Incidental Metastatic Lymph Nodes” authored by Alameer et al has attracted my attention. Of 74 patients (most are classified as intermediate risk per the American Thyroid Association) with localized thyroid cancer with low-volume incidental N1a metastases treated by lobectomy or isthmectomy, recurrence-free survival, disease-specific survival, and overall survival were 97.4%, 100%, and 96.2%, respectively.

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Monitoring Thyroglobulin Following Total Thyroidectomy After Lobectomy—Reply

E Alameer,A Eagan,I Ganly

Publication date 01-04-2024


In Reply We thank Chow for their interest in our recent article. As they note, of 74 patients (most classified as intermediate risk per the American Thyroid Association) with localized thyroid cancer with low-volume incidental N1a metastases treated by lobectomy or isthmectomy, recurrence-free survival, disease-specific survival, and overall survival were 97.4%, 100%, and 96.2%, respectively.

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Prognostic Factors for Survival Among Patients With Acute Invasive Fungal Sinusitis

MA Munyemana,D Kallogjeri,R Chernock,NF Farrell,JS Schneider,JF Piccirillo,LT Roland

Publication date 01-04-2024


This cohort study identifies prognostically important factors in acute invasive fungal sinusitis and incorporates the factors into a comprehensive functional severity staging system and clinical severity staging system.

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Pediatric Tracheostomy

D Lam,G Tan

Publication date 01-04-2024


This Patient Page describes the use of tracheostomy in the pediatric population.

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Evaluating Head and Neck Reconstruction Outcomes Proves Difficult

FC Wei,JL Harrison,AP Calimag

Publication date 01-04-2024


This Viewpoint advocates for the improvement of the quality of head and neck reconstruction studies through accurate depictions of the defect and reconstruction performed.

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Patient With Dysphonia

CH Ng,M Rahman,EJ Damrose

Publication date 01-04-2024


A male individual in his 60s presented with a hoarse and weak voice and a history of follicular lymphoma with multiple relapses treated with an allogeneic stem cell transplant complicated by graft-vs-host disease treated with sirolimus and steroids. What is your diagnosis?

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A Rare Case of Sudden Massive Neck Tumor

J Zhang,X Zhu

Publication date 01-04-2024


A 23-year-old male patient sought evaluation at the vascular thyroid surgery clinic for a large neck tumor that appeared abruptly 10 days prior. What is your diagnosis?

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The Future of Endoscopic Endonasal Surgical Navigation

BR Rosvall,GW Choby

Publication date 01-04-2024


In their case series study, Bartholomew et al assessed the accuracy and potential clinical utility of a trackerless surgical navigation system using 3-dimensional (3D) endoscopy and simultaneous localization and mapping (SLAM) algorithms in the anterior cranial base, perhaps setting the stage for a paradigm shift in the registration of surgical navigation devices. The use of intraoperative navigation has been widely adopted in endoscopic endonasal surgery to help accurately identify intraoperative anatomy and has been endorsed by the American Academy of Otolaryngology–Head and Neck Surgery. Although it is not a substitute for knowledge of surgical anatomy, surgical navigation may reduce total and major complications during endoscopic endonasal surgery while simultaneously improving surgeon confidence and enabling more complete surgery.

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Surgical Navigation in the Anterior Skull Base Using 3-Dimensional Endoscopy and Surface Reconstruction

RA Bartholomew,H Zhou,M Boreel,K Suresh,S Gupta,MB Mitchell,C Hong,SE Lee,TR Smith,JP Guenette,CE Corrales,J Jagadeesan

Publication date 01-04-2024


This case series study evaluates a trackerless surgical navigation system using 3-dimensional endoscopy and simultaneous localization and mapping algorithms in the anterior skull base.

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Functional Laryngectomy and Quality of Life in Survivors of Head and Neck Cancer

L Evangelista,N Nativ-Zeltzer,A Bewley,AC Birkeland,M Abouyared,M Kuhn,DJ Cates,DG Farwell,P Belafsky

Publication date 01-04-2024


This cohort study assesses the association of functional laryngectomy with self-perceptions of voice, swallowing, oral intake, quality of life, and mood among survivors of head and neck cancer experiencing intractable aspiration.

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Use of Open-Source, Low-Cost, Flexible Laryngoscope for Resource-Limited Settings

Y Srinivasan,D Shamritsky,A Bhatta,E Chou,T Pham,Y Sanghvi,L Woolf,M Zhang,E Odigie,C Chidziva,E Muganda,P Zimani,N de Faria,A Rameau

Publication date 01-04-2024


This quality improvement study describes the development of a novel low-cost flexible laryngoscope and the evaluation of the device by expert otolaryngologists.

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Use of Diagnostic Audiology and Cochlear Implantation in the US

KY Zhan,A Mazul,DL Kallogjeri,CA Buchman

Publication date 01-04-2024


This study examined if cochlear implant (CI) use varies geographically within the US and if diagnostic audiology use correlates with CI usage.

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Neighborhood Deprivation and Symptoms, Psychological Distress, and Quality of Life for HNC Survivors

Z Balogun,LA Gardiner,J Li,EA Moroni,M Rosenzweig,ML Nilsen

Publication date 01-04-2024


This cross-sectional study assesses whether neighborhood socioeconomic condition is associated with symptom burden, psychological distress, and quality of life among head and neck cancer (HNC) survivors.

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Patient Experience of Head and Neck Surgery With Free Flap Reconstruction

LW Dattilo,TI Russell,CB Warinner,H Starmer,DJ Annino,LA Goguen,RKV Sethi,R Uppaluri,MJ Windon,RW Bergmark,EM Rettig

Publication date 01-04-2024


This qualitative study characterizes preoperative decision-making, patient experiences of surgery and recovery, and decision regret for the unique population of patients undergoing free flap reconstruction for head and neck cancer defects.

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Voice as an AI Biomarker of Health—Introducing Audiomics

Y Bensoussan,O Elemento,A Rameau

Publication date 01-04-2024


This Viewpoint discusses the need to create standards for audiomics to identify unique audio biomarkers of health and disease—now possible because of more efficient voice data analysis available through the use of artificial intelligence (AI)—and to improve patient care.

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Error in Author Credentials

Publication date 01-04-2024


The Original Investigation titled “Oral Human Papillomavirus Prevalence and Genotyping Among a Healthy Adult Population in the US,” published in the September 2023 print issue, included an error in the byline. The credentials for the sixth author Craig Roberts are edited from PhD to PharmD, MPA, MBA. This article has been corrected online.

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Tooth Extraction and Osteoradionecrosis

E Topkan,E Somay,U Selek

Publication date 01-04-2024


To the Editor Lee and colleagues should be commended for investigating whether the timing of tooth extraction (TE) before radiotherapy (RT) is associated with osteoradionecrosis (ORN) in 879 patients with head and neck cancer (HNC). This retrospective cohort study revealed a significant association between ORN and pre-RT TEs performed within 7 days of starting RT. However, because only 16 patients (1.8%) developed ORN, the authors recommended against delaying RT due to TEs. However, we have 2 notable concerns to be addressed.

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Physical Therapy and Risk of Falls Among Patients With Dizziness

HT Wu,CC Tung,R Chang

Publication date 01-04-2024


To the Editor We read with interest the epidemiological study by Marmor et al who delved into the association between receipt of physical therapy (PT) and falls requiring medical care within 12 months of presentation for dizziness. Using a multivariable regression with a separate multivariable model, the study indicated that timely physical therapy referral for dizziness could be associated with a reduction in the risk of injurious falls, with the greatest risk reduction found within 3 months after PT (adjusted odds ratio AOR, 0.14; 95% CI, 0.14-0.15 at 3-12 months vs 0.18; 95% CI, 0.18-0.19 at 6-12 months and 0.23; 95% CI, 0.23-0.24 at 9-12 months). We would like to share some ideas regarding their article.

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Tooth Extraction and Osteoradionecrosis—Reply

E Watson,JH Lee,A Hosni

Publication date 01-04-2024


In Reply We thank Topkan et al for their thoughtful and insightful comments on our recent publication titled “Dental Extractions Before Radiation Therapy and the Risk of Osteoradionecrosis in Patients With Head and Neck Cancer.” We appreciate their engagement with our work and welcome the opportunity to address the concerns raised.

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Physical Therapy And Risk of Falls Among Patients With Dizziness—Reply

S Marmor,P Karaca-Mandic,ME Adams

Publication date 01-04-2024


In Reply We thank Wu and colleagues for their insightful comments about our study that assessed the use of physical therapy (PT) and subsequent falls among patients with dizziness in the US using a large administrative claims dataset. Our primary objective was to examine the association between receipt of any PT service and falls requiring medical care within 12 months of presentation for dizziness, and secondarily to identify factors associated with receipt of PT and falls. In their Letter, Wu and colleagues emphasize the potential influence of several unmeasured variables on the observed association. We concur with the authors regarding the potential significance of the patient-specific factors they mention, including frailty, general balance, and mobility, as well as the capacity and willingness to adhere to the recommended PT regimen during and after therapy sessions at home as important covariates. At the same time, we acknowledge constraints in assessing these variables in our analyses due to their unavailability in the administrative dataset we used. We agree with the authors on the necessity for further research to elucidate how these variables may affect PT use and the effects of PT for patients experiencing dizziness.

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Salvage Microsurgery Following Failed Primary Radiosurgery in Sporadic Vestibular Schwannoma

JP Marinelli,HA Herberg,LS Moore,KL Yancey,E Kay-Rivest,GG Casale,A Durham,KR Khandalavala,M Lund-Johansen,N Kosaraju,CM Lohse,NS Patel,RK Gurgel,SC Babu,JG Golfinos,JT Roland,JB Hunter,JW Kutz,PL Santa Maria,MJ Link,ØV Tveiten,ML Carlson

Publication date 01-04-2024


This cohort study describes the clinical outcomes of salvage microsurgery following failed primary stereotactic radiosurgery or fractionated stereotactic radiotherapy among patients with sporadic vestibular schwannoma.

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Causes and Ways of Death in Patients With Head and Neck Cancer

BN van den Besselaar,A Sewnaik,A Hoesseini,MC Dorr,RJ Baatenburg de Jong,MPJ Offerman

Publication date 01-04-2024


This cohort study examines the causes and ways of death among Dutch patients with head and neck cancer.

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