Acta Oto Laryngologica

Acta Oto Laryngologica

Canalostomy is an ideal surgery route for inner ear gene delivery in big animal model

06-09-2019 – Xiao-Jun Ji,Wei Chen,Xiao Wang,Yue Zhang,Qian Liu,Wei-Wei Guo,Jian-Guo Zhao,Shi-Ming Yang

Journal Article

Inner gene therapy offers great promises as a potential treatment for hearing loss.

Localization of melatonin and its receptors (melatonin 1a and 1b receptors) in the mouse inner ear

29-09-2019 – Masaya Takumida,Matti Anniko

Journal Article

In the inner ear, evidence has been gathered indicating that melatonin plays important roles in inner ear physiology and pathophysiology. However, no attempt has been made previously to investigate the localization or expression of melatonin and its receptors in the whole inner ear.

Current state of evidence for endolymphatic sac surgery in Menière’s disease: a systematic review

10-09-2019 – Louise Devantier,Jesper Hvass Schmidt,Bjarki Ditlev Djurhuus,Dan Dupont Hougaard,Mina Nicole Händel,Frank Liviu-Adelin Guldfred,Henriette Edemann-Callesen

Journal Article

Endolymphatic sac surgery is an invasive procedure recommended to patients with Menière’s disease.

Characteristics and prognosis of idiopathic sudden sensorineural hearing loss in aged people: a retrospective study

10-09-2019 – Chengfang Chen,Guanggang Shi,Mingqiang He,Xinlei Song,Xueqing Cheng,Baowei Wang,Hongbo Gu,Xuhui Liang,Shudong Yu

Journal Article

Few studies focused on the prognosis of sudden sensorineural hearing loss (ISSHL) of aged people.

“Solute carrier family 4 member 1 might participate in the pathogenesis of Menieres disease in a murine endolymphatic hydrop model”

20-09-2019 – Shujuan Sun,Daogong Zhang,Gaoying Sun,Yongdong Song,Jing Cai,Zhaomin Fan,Haibo Wang

Journal Article

To date, the pathogenesis of Meniere’s disease (MD) remains unclear. Previous research found that the SLC4A1 gene significantly down-regulated.

Are Meniere’s disease patients with otolith organ impairment more likely to have balance dysfunction?

20-09-2019 – Yu-Juan Zhou,Qing-Zhong Li,Ying-Qi Gao,Lin-Xi Gao,Zhi-Xiang Zhao,Yong-Zhen Wu,Jing Wang

Journal Article

Patients with Meniere’s disease (MD) may present with peripheral vestibular end organ dysfunction and balance dysfunction.

Intratympanically administered steroid for progressive sensorineural hearing loss in Ménière’s disease

10-09-2019 – András Molnár,Stefani Maihoub,László Tamás,Ágnes Szirmai

Journal Article

Ménière’s disease is characterised by episodic rotational vertigo, sensorineural hearing loss, tinnitus, and vegetative symptoms.

Main sequence of torsional saccadic eye movement – analysis by three-dimensional video-oculography

13-09-2019 – Ayame Yamazaki,Takuo Ikeda,Takeshi Tsutsumi

Journal Article

Quantification of main sequence is required for three-dimensional recording and analysis of eye movement using video-oculography. However, the main sequence of torsional saccade has not been reported to the best of our knowledge.

Speech development after cochlear implantation in infants with isolated large vestibular aqueduct syndrome

26-09-2019 – Yang Li,Ying Kong,Tianqiu Xu,Ruijuan Dong,Jing Lv,Beier Qi,Shuo Wang,Fei Yan,Yongxin Li,Mo Long,Xueqing Chen

Journal Article

Few studies on speech performance of children after cochlear implantation (CI) described isolated large vestibular aqueduct syndrome (LVAS).

A new and simple test for diagnosis and prognosis in children with otitis media with effusion: cVEMP

30-08-2019 – Erkan Yıldız,Abdulkadir Bucak,Selçuk Kuzu

Journal Article

A typical vestibular stimulated myogenic potential (VEMP) response depends on suitable sound transfer from the middle ear to inner ear. This transfer is degraded at various degrees in otitis media with effusion (OME). In cases where the effusion is reduced by treating the OME, response to VEMP test can be obtained

Sudden sensorineural hearing loss with end-stage renal disease: a report of 32 cases

06-09-2019 – Xiangsheng Wang,Ruirui Jiang,Jiang Su

Journal Article

Patients with end-stage renal disease (ESRD) have a higher risk of suffering sudden sensorineural hearing loss (SSNHL), but little is known about this population.

Is auditory brainstem response a prognostic factor in patients with sudden sensorineural hearing loss?

13-09-2019 – Hye-Jeong Heo,Chul-Hee Choi,Sung Hwa Hong,Sihyung Kang,Myung Gu Kim,Young-Soo Chang

Journal Article

Serum thyroid hormone levels are closely related to the normal functioning of the cochlea. However, the relationship between initial auditory brainstem response (ABR) results and levels of thyroid hormone remained unclear until we adopted ABR as a prognostic factor in Idiopathic sudden sensorineural hearing loss (ISSNHL) patients.

Effect of vibration on the vestibular system in noisy and noise-free environments in heavy industry

20-09-2019 – Nihat Yilmaz,Kadri Ila

Journal Article

Chronic exposure to whole body vibration can affect the gastrointestinal system, the lumbar spine, the peripheral veins and the vestibulocochlear system.

Human papillomavirus and infiltration of CD8- and Foxp3-positive immune cells in sinonasal inverted papillomas

06-09-2019 – Alexandra Elliot,Anders Näsman,Marit Westman,Linda Marklund,Pär Stjärne,Lalle Hammarstedt-Nordenvall

Journal Article

Sinonasal inverted papilloma (IP) is a benign tumor with a high risk of local recurrence and a potential to malignify and Human papillomavirus (HPV) has been suggested an etiological factor. p16INK4a (p16) overexpression is considered a surrogate marker for HPV, but whether p16 and HPV correlate to IP is uncertain. Besides, a prognostic role of tumor infiltrating lymphocytes (TILs) are observed in many tumors, however their role in IP is sparsely studied.

Dynamic soft tissue changes in the orbit after a blowout fracture

10-09-2019 – Ulrik Ascanius Felding,Olaf E. Damgaard,Sune L. Bloch,Tron A. Darvann,Carsten Thomsen,Peter B. Toft,Christian von Buchwald

Journal Article

The intraorbital contents are thought to be affected by oedema in the days following a blowout fracture. We posit that this oedema can be detected by Magnetic resonance imaging (MRI) as changes in muscle volume, in muscle cross-sectional area, and in the MRI parameter ‘mean grey value’ (MGV) of the orbital fat and extraocular muscles (EOMs).

High CT attenuation values relative to the brainstem may predict squamous cell carcinoma arising from inverted papilloma

10-09-2019 – Sanami Azuma,Shu Kikuta,Masafumi Yoshida,Mizuo Ando,Kenji Kondo,Tatsuya Yamasoba

Journal Article

A diagnostic indicator for differentiating squamous cell carcinomas (SCCs) from inverted papillomas (IPs) has not been established.

Perineural invasion as a prognostic factor in head and neck squamous cell carcinoma: a systematic review and meta-analysis

30-08-2019 – Jing Zhu,Rui Zhou,Yihan Wang,Min Yu

Journal Article

Squamous cell carcinoma (SCC) is the most common type of head and neck cancer, and head and neck squamous cell carcinoma (HNSCC) was proved to having a high prevalence of perineural invasion (PNI). Although some reports have revealed a relationship between PNI and the prognosis in HNSCC patients, the contribution of PNI to the prognosis remains unclear.

Utilization of incus with bone cement for total ossicular reconstruction

28-08-2019 – Emine Demir,Engin Dursun

Journal Article

Total ossicular chain reconstructions are performed to connect mobile stapes footplate and tympanic membrane. Data on the use of incus for total ossicular reconstruction is quite limited in the literature.

Total facial nerve decompression in severe idiopathic recurrent facial palsy: its long-term follow-up results

26-09-2019 – Fang Xing,Yudan Ouyang,Xiaowen Li

Journal Article

The long-term outcomes of total facial nerve decompression (TFND) in severe idiopathic recurrent facial palsy (IRFP) are still unknown.

Predictors of hearing outcomes after stapes surgery in otosclerosis

17-10-2019 – Chien-Fu Yeh,Mao-Che Wang,Chia-Huei Chu,An-Suey Shiao

Journal Article

The current surgical treatment of otosclerosis is stapes surgery; however, few studies have reported the predictors of surgical outcomes.

Can the bending forward test be used to detect a diseased anterior semi-circular canal in patients with chronic vestibular multi-canalicular canalithiasis (BPPV)?

08-10-2019 – Wenche Iglebekk,Carsten Tjell,Peter Borenstein

Journal Article

Patients with chronic vestibular multi-canalicular canalithiasis (CVMCC) can have serious morbidities, for example, musculoskeletal pain, dizziness, fatigue, and cognitive difficulties. Involvement of the anterior semi-circular canal (SCC) is common in CVMCC. A mono-canalicular diseased anterior SCC is rare.

Progression of hearing loss and choice of hearing aids by patients in their 60s, 70s, and 80s and older: experience in the Japanese super-aged era

29-09-2019 – Yukihide Maeda,Shin Kariya,Shohei Fujimoto,Akiko Sugaya,Yuko Kataoka,Atsuko Nakagawa,Satomi Tanaka,Natsumi Hosokawa,Kazunori Nishizaki

Journal Article

Demographic data of patients with sensorineural hearing loss (SNHL) in super-aged societies are still limited.

Sandwich technique for sigmoid sinus wall reconstruction for treatment of pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence

29-09-2019 – Jiaqiang Sun,Jingwu Sun

Journal Article

If the pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence cannot be diagnosed and treated, it can lead to significant morbidity and mortality.

Current status of human papillomavirus positivity in oropharyngeal squamous cell carcinoma in Europe: a systematic review

29-09-2019 – Karoline Dyrberg Stjernstrøm,Jakob Schmidt Jensen,Kathrine Kronberg Jakobsen,Christian Grønhøj,Christian von Buchwald

Journal Article

The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been rising in the Western world in recent years. Human papillomavirus (HPV) infection is established as the main explanation.

Comparative outcomes of extracapsular dissection and superficial parotidectomy

29-09-2019 – Kerem Ozturk,Arin Ozturk,Goksel Turhal,Isa Kaya,Serdar Akyildiz,Umit Uluoz

Journal Article

Retrospective analysis of extracapsular dissection (ECD) and superficial parotidectomy (SP).

Comparison of the development of early auditory and preverbal skills in Mandarin-Speaking children with cochlear implants with and without additional disabilities

29-09-2019 – Yawen Zhao,Ying Li,Yue Long,Xin Jin,Zhipeng Zheng,Yidi Liu,Ying Wang,Jun Zheng,Jie Zhang,Min Chen,Jinsheng Hao,Yang Yang,Wei Liu,Haihong Liu,Xin Ni

Journal Article

Few studies had assessed the auditory and preverbal skills of very young cochlear implant (CI) children with additional disabilities (AD) over a long period, especially in China.

ErbB1 and ErbB2 overexpression in patients with sinonasal inverted papilloma and inverted papilloma with squamous cell carcinoma in China

27-09-2019 – Hongbing Li,Li Hu,Huankang Zhang,Dehui Wang

Journal Article

Currently, the expression patterns of epidermal growth factor receptor (EGFR) family genes in sinonasal inverted papilloma (SNIP) and inverted papilloma with squamous cell carcinoma (IPw
SCC) are not clear.

Therapeutic efficacy of intralesional bleomycin injection for laryngopharyngeal haemangioma in adults

27-09-2019 – Feifei Liu,Yang Xiao,Jun Wang

Journal Article

Head and neck haemangiomas in the pharynx and larynx are rare, and the injection of bleomycin is currently one of the effective treatments. However, data on the therapeutic efficacy of this treatment are scarce.

Efficacy of microsurgery in combined with topical-PDT in treating recurrent respiratory papillomatosis: compare JORRP with AORRP

27-09-2019 – Shuzhi Yang,Chengyong Zhou,Baochun Sun,Feng Wang,Zeli Han,Hongjia Zhang,Jiahong Han,Yao Shen,Jiao Zhang

Journal Article

Recurrent respiratory papillomatosis (RRP) remains a challenging and frustrating disease to treat.

Clinical long-term effects of surgical treatment for intractable Meniere’s disease: a more than 13-year follow-up after pressure treatment and further surgical treatment for intractable vertigo

27-09-2019 – Fang Liu,Weining Huang,Kai Chen

Journal Article

Meniere’s disease appears to be a complex inner ear disorder and also remains a controversial and often difficult disease as regards determination of diagnosis, pathogenesis and especially optimal treatment.

Dose- and starting time-dependent effect of the application of EGF to the regeneration of traumatic eardrum

26-09-2019 – Zheng Cai Lou

Journal Article

Some studies have shown that topical application of epidermal growth factor (EGF) accelerates healing in traumatic tympanic membrane perforations (TMPs), however, the optimal dose and starting time of application have not been established.